Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8796899 | 0.92 | GAA (0.38) | MAPTKMT2AMAOBHRH3TNIK | |
| SCHEMBL8797305 | 0.91 | HRH3 (0.36) | MAPTMEN1KMT2ASMN1; SMN2MAOB | |
| SCHEMBL8797166 | 0.90 | BCHE (0.38) | KMT2AHRH3 | |
| SCHEMBL8797483 | 0.90 | POLB (0.35) | ROCK2ROCK1MAPTKMT2AMAOB | |
| SCHEMBL8797318 | 0.89 | ESR1 (0.37) | — | |
| SCHEMBL8797289 | 0.89 | HRH3 (0.36) | ROCK2ROCK1MAPTMEN1KMT2A | |
| SCHEMBL8797027 | 0.88 | HRH3 (0.36) | MAPTMEN1KMT2AMAOBFFAR1 | |
| SCHEMBL6953755 | 0.88 | HRH3 (0.40) | MAOBFFAR1HRH3HPGDPPARG | |
| SCHEMBL8796841 | 0.87 | HRH3 (0.39) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8797688 | 0.87 | HRH3 (0.35) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787727-A1 | Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same | SS Pharmaceutical Co., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |