Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797305 | 0.96 | HRH3 (0.36) | HRH3MAPTALDH1A1KMT2APOLB | |
| SCHEMBL8798105 | 0.88 | HRH3 (0.44) | HRH3MAPTPOLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL8797264 | 0.87 | ROCK2 (0.38) | HRH3MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL8796899 | 0.86 | GAA (0.38) | HRH3MAPTALDH1A1KMT2APOLB | |
| SCHEMBL8797027 | 0.86 | HRH3 (0.36) | HRH3MAPTALDH1A1KMT2APOLB | |
| SCHEMBL8797206 | 0.85 | HRH3 (0.38) | HRH3POLBL3MBTL1TDP1KDM4A | |
| SCHEMBL8797483 | 0.85 | POLB (0.35) | HRH3MAPTALDH1A1KMT2APOLB | |
| SCHEMBL8796918 | 0.85 | HRH3 (0.38) | HRH3KMT2APOLBL3MBTL1KDM4A | |
| SCHEMBL8797318 | 0.85 | ESR1 (0.37) | — | |
| SCHEMBL8797248 | 0.85 | HRH3 (0.37) | HRH3MAPTALDH1A1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787727-A1 | Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same | SS Pharmaceutical Co., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |