Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 18/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8689723 | 1.00 | SLC10A2 (0.37) | SLC10A2SLC6A9NQO2MTNR1AMTNR1B | |
| SCHEMBL8228239 | 0.88 | SLC10A2 (0.44) | SLC10A2 | |
| SCHEMBL8228241 | 0.88 | SLC10A2 (0.44) | SLC10A2 | |
| SCHEMBL8694201 | 0.88 | SLC10A2 (0.37) | SLC10A2SLC6A9 | |
| SCHEMBL8797907 | 0.88 | SLC10A2 (0.37) | SLC10A2SLC6A9 | |
| SCHEMBL8194080 | 0.84 | SLC10A2 (0.42) | SLC10A2 | |
| SCHEMBL8693241 | 0.82 | SLC6A9 (0.36) | SLC10A2SLC6A9NQO2MTNR1AMTNR1B | |
| SCHEMBL7482516 | 0.82 | SLC10A2 (0.37) | SLC10A2 | |
| SCHEMBL7482510 | 0.82 | SLC10A2 (0.37) | SLC10A2 | |
| SCHEMBL8798356 | 0.82 | SLC6A9 (0.36) | SLC10A2SLC6A9NQO2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683773-B1 | HYPOLIPIDAEMIC CONDENSED 1,4-THIAZEPINES | WELLCOME FOUND (GB) | 1997-09-17 | — | — | EP | disclosed |
| EP-0683773-A1 | HYPOLIPIDAEMIC CONDENSED 1,4-THIAZEPINES. | WELLCOME FOUND (GB) | 1995-11-29 | — | — | EP | disclosed |
| WO-1994018183-A1 | HYPOLIPIDAEMIC CONDENSED 1,4-THIAZEPINES | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-08-18 | — | — | WO | disclosed |