Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 8/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797324 | 0.90 | MGAM (0.56) | MGAMGAASIMGAM2HPGD | |
| SCHEMBL8797320 | 0.90 | MGAM (0.56) | MGAMGAASIMGAM2HPGD | |
| SCHEMBL8796992 | 0.83 | HPGD (0.42) | HPGDMAOAMAOBACHE | |
| SCHEMBL8797391 | 0.80 | CSNK2A2 (0.47) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL8796784 | 0.80 | MGAM (0.46) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL9143115 | 0.80 | MGAM (0.60) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL8797031 | 0.77 | MGAM (0.45) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL8796972 | 0.76 | HRH3 (0.37) | HPGDHRH3 | |
| SCHEMBL8796971 | 0.76 | PPARG (0.54) | HPGDHRH3 | |
| SCHEMBL9326985 | 0.74 | CSNK2A2 (0.62) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787727-A1 | Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same | SS Pharmaceutical Co., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |