Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 8/20 | 0.38 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797324 | 0.84 | MGAM (0.56) | HPGDMAOBMAOA | |
| SCHEMBL8797320 | 0.84 | MGAM (0.56) | HPGDMAOBMAOA | |
| SCHEMBL8797330 | 0.83 | CSNK2A2 (0.46) | HPGDACHEMAOBMAOA | |
| SCHEMBL8576743 | 0.83 | ALDH1A1 (0.46) | HPGDNPSR1RAB9AALDH1A1MAPT | |
| SCHEMBL8796971 | 0.77 | PPARG (0.54) | HPGDALDH1A1MAPT | |
| SCHEMBL8796972 | 0.75 | HRH3 (0.37) | HPGDNPSR1RAB9AALDH1A1MAPT | |
| SCHEMBL8796640 | 0.75 | RAB9A (0.44) | HPGDNPSR1RAB9AACHEALDH1A1 | |
| SCHEMBL6949825 | 0.74 | ACHE (0.45) | HPGDNPSR1RAB9AACHENPC1 | |
| SCHEMBL30084003 | 0.73 | HPGD (0.70) | HPGDNPSR1RAB9AALDH1A1MAPT | |
| SCHEMBL8577393 | 0.73 | NPSR1 (0.41) | HPGDNPSR1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787727-A1 | Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same | SS Pharmaceutical Co., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |