Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.62 |
| ▸ | CLK1 | P49759 | 1/20 | 0.62 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.62 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.62 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.62 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.62 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 11/20 | 0.59 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433166 | 0.89 | HPGD (0.75) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL9803959 | 0.86 | CSNK2A2 (0.62) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL9327176 | 0.84 | PPARG (0.64) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL9326177 | 0.84 | HPGD (0.80) | HPGDCISD1PTPN1MAOAMAOB | |
| SCHEMBL9326976 | 0.84 | HPGD (0.80) | HPGDCISD1PTPN1MAOAMAOB | |
| SCHEMBL4156417 | 0.83 | CSNK2A2 (0.65) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL9143115 | 0.82 | MGAM (0.60) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL9311896 | 0.81 | HPGD (0.58) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL9534313 | 0.81 | CSNK2A2 (0.46) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL9430658 | 0.81 | HPGD (0.51) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415605-B1 | Thiazolidinedione derivatives | BEECHAM GROUP PLC (GB) | 1994-03-02 | — | — | EP | claimed |
| EP-0415605-A1 | Thiazolidinedione derivatives | Beecham Group p.l.c. (GB) | 1991-03-06 | — | — | EP | claimed |
| JP-3090071-A | — | — | None | — | — | JP | disclosed |
| EP-0415605-B1 | Thiazolidinedione derivatives | BEECHAM GROUP PLC (GB) | 1994-03-02 | — | — | EP | disclosed |
| US-5132317-A | Thiazolidinediones, Hypoglycemia Agents | BEECHAM GROUP P.L.C. (GB) | 1992-07-21 | — | — | US | disclosed |
| JP-H0390071-A | NEW COMPOUND, ITS PRODUCTION AND PHARMACEUTICAL COMPOSITION | BEECHAM GROUP PLC | 1991-04-16 | — | — | JP | disclosed |
| EP-0415605-A1 | Thiazolidinedione derivatives | Beecham Group p.l.c. (GB) | 1991-03-06 | — | — | EP | disclosed |