Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1038751 | 0.88 | NAAA (0.43) | NAAAALDH1A1MAPK1ATMHCAR2 | |
| SCHEMBL7066411 | 0.84 | SLC1A1 (0.58) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28342779 | 0.83 | NAAA (0.50) | NAAAALDH1A1MAPK1HCAR2MAPT | |
| SCHEMBL9067257 | 0.83 | MME (0.51) | ALDH1A1MME | |
| SCHEMBL8798162 | 0.83 | CHRM1 (0.52) | NAAAALDH1A1SLC1A3SLC1A2MAPK1 | |
| SCHEMBL1061357 | 0.83 | CA2 (0.55) | NAAAALDH1A1SLC1A3SLC1A2MAPK1 | |
| SCHEMBL8047058 | 0.82 | SLC1A3 (0.46) | ALDH1A1SLC1A3SLC1A2MMECPA1 | |
| SCHEMBL5558434 | 0.82 | SLC1A3 (0.46) | ALDH1A1SLC1A3SLC1A2MMECPA1 | |
| SCHEMBL2637671 | 0.82 | SLC1A3 (0.46) | ALDH1A1SLC1A3SLC1A2MMECPA1 | |
| SCHEMBL8669263 | 0.81 | NAAA (0.60) | NAAAMAPK1HCAR2MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807114-A1 | BRIDGED INDOLES AS MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996023791-A1 | BRIDGED INDOLES AS MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1996-08-08 | — | — | WO | disclosed |