SCHEMBL8797385

SCHEMBL8797385

CC1Oc2ccccc2C(=O)N1CCOc1ccc(/C=C2\SC(=O)NC2=O)cc1

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.55
GAA P10253 1/20 0.55
SI P14410 1/20 0.55
MGAM2 Q2M2H8 1/20 0.55
HPGD P15428 11/20 0.55
PIM1 P11309 2/20 0.53
PIM2 Q9P1W9 2/20 0.53
MAOA P21397 2/20 0.52
MAOB P27338 2/20 0.52
CISD1 Q9NZ45 3/20 0.49
HRH3 Q9Y5N1 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8797389 1.00 MGAM (0.55) MGAMGAASIMGAM2HPGD
SCHEMBL8797391 0.90 CSNK2A2 (0.47) MGAMGAASIMGAM2HPGD
SCHEMBL8796640 0.83 RAB9A (0.44) HPGDMAOAMAOB
SCHEMBL8797320 0.80 MGAM (0.56) MGAMGAASIMGAM2HPGD
SCHEMBL8797324 0.80 MGAM (0.56) MGAMGAASIMGAM2HPGD
SCHEMBL8796772 0.80 MGAM (0.58) MGAMGAASIMGAM2HPGD
SCHEMBL6358097 0.80 PIM1 (0.56) MGAMGAASIMGAM2HPGD
SCHEMBL7454718 0.80 MGAM (0.58) MGAMGAASIMGAM2HPGD
SCHEMBL9143110 0.78 MGAM (0.78) MGAMGAASIMGAM2HPGD
SCHEMBL9143106 0.78 MGAM (0.78) MGAMGAASIMGAM2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0787727-A1 Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same SS Pharmaceutical Co., Ltd. (JP) 1997-08-06 EP disclosed