Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.56 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 10/20 | 0.55 |
| ▸ | MGAM | O43451 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | SI | P14410 | 1/20 | 0.55 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797385 | 0.80 | MGAM (0.55) | PIM1PIM2HPGDMGAMGAA | |
| SCHEMBL8797389 | 0.80 | MGAM (0.55) | PIM1PIM2HPGDMGAMGAA | |
| SCHEMBL9143106 | 0.79 | MGAM (0.78) | PIM1PIM2HPGDMGAMGAA | |
| SCHEMBL9143110 | 0.79 | MGAM (0.78) | PIM1PIM2HPGDMGAMGAA | |
| SCHEMBL8797068 | 0.78 | MGAM (0.58) | PIM1PIM2HPGDMGAMGAA | |
| SCHEMBL8128807 | 0.77 | HPGD (0.61) | PIM1PIM2HPGDMGAMGAA | |
| Hydrochloric Acid SCHEMBL8128709 | 0.76 | HPGD (0.60) | PIM1PIM2HPGDMGAMGAA | |
| SCHEMBL9326177 | 0.75 | HPGD (0.80) | PIM1PIM2HPGDMAOAMAOB | |
| SCHEMBL9326976 | 0.75 | HPGD (0.80) | PIM1PIM2HPGDMAOAMAOB | |
| SCHEMBL8120013 | 0.75 | HPGD (0.60) | PIM1PIM2HPGDMGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050032864-A1 | Novel heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases | DR. REDDY'S LABORATORIES LIMITED | 2005-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032864-A1 | Novel heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases | IAPP, GPR119, CYP11B2 | PIM1 2301/4885PIM2 2769/4885HPGD 489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.