Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 17/20 | 0.59 |
| ▸ | ITGA2 | P17301 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798644 | 0.92 | ITGB3 (0.58) | ITGB3ITGA2BITGA2ALDH1A1GRM4 | |
| SCHEMBL8797895 | 0.90 | ITGB3 (0.56) | ITGB3ITGA2BITGA2ALDH1A1GRM4 | |
| SCHEMBL8798269 | 0.90 | ITGB3 (0.56) | ITGB3ITGA2BITGA2GRM4 | |
| SCHEMBL8798937 | 0.89 | ITGB3 (0.73) | ITGB3ITGA2BITGA2ALDH1A1 | |
| SCHEMBL8798194 | 0.87 | ITGB3 (0.56) | ITGB3ITGA2BITGA2ALDH1A1GRM4 | |
| SCHEMBL8798130 | 0.86 | ITGB3 (0.80) | ITGB3ITGA2BITGA2ALDH1A1GRM4 | |
| SCHEMBL8798079 | 0.85 | ITGB3 (0.54) | ITGB3ITGA2BITGA2GRM4 | |
| SCHEMBL8797709 | 0.80 | ITGB3 (0.72) | ITGB3ITGA2BITGA2ALDH1A1 | |
| SCHEMBL8798139 | 0.78 | ITGB3 (0.69) | ITGB3ITGA2BITGA2 | |
| SCHEMBL8798242 | 0.78 | ITGB3 (0.69) | ITGB3ITGA2BITGA2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708775-B1 | TRICYCLIC INHIBITORS OF THE GPII b III a RECEPTOR | GENENTECH INC (US) | 1997-05-28 | — | — | EP | claimed |
| EP-0708775-A1 | TRICYCLIC INHIBITORS OF THE GPII b III a RECEPTOR | GENENTECH INC (US) | 1996-05-01 | — | — | EP | claimed |
| EP-0708775-B1 | TRICYCLIC INHIBITORS OF THE GPII b III a RECEPTOR | GENENTECH INC (US) | 1997-05-28 | — | — | EP | disclosed |
| US-5493020-A | ANTICOAGULANTS | GENENTECH, INC. (US) | 1996-02-20 | — | — | US | disclosed |