Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | MPC2 | O95563 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797412 | 0.89 | FFAR1 (0.39) | HRH3ROCK2PPARGFFAR1CHRM5 | |
| SCHEMBL8797614 | 0.89 | MAOB (0.36) | HRH3PPARGFFAR1KDM4AUSP2 | |
| SCHEMBL8797065 | 0.87 | HRH3 (0.41) | HRH3PPARGFFAR1RAB9A | |
| SCHEMBL8798566 | 0.86 | SNCA (0.35) | HRH3LMNAPOLB | |
| SCHEMBL8797598 | 0.83 | PPARG (0.52) | HRH3PPARGFFAR1MPC2CYP2C8 | |
| SCHEMBL8797333 | 0.83 | HRH3 (0.45) | HRH3PPARGFFAR1RAB9AKDM4A | |
| SCHEMBL8797062 | 0.82 | PPARG (0.36) | HRH3ROCK2PPARGFFAR1RAB9A | |
| SCHEMBL8797264 | 0.82 | ROCK2 (0.38) | HRH3ROCK2PPARGFFAR1ROCK1 | |
| SCHEMBL8797166 | 0.78 | BCHE (0.38) | HRH3 | |
| SCHEMBL8797027 | 0.76 | HRH3 (0.36) | HRH3PPARGFFAR1LMNAKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787727-A1 | Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same | SS Pharmaceutical Co., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |