Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | HTR1F | P30939 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 6/20 | 0.46 |
| ▸ | HTR1A | P08908 | 5/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL7865145 | 0.95 | LMNA (0.56) | KDM4ELMNAALOX15HTR1FDRD2 | |
| Phosphoric Acid SCHEMBL7868050 | 0.87 | KDM4E (0.56) | KDM4ELMNAALOX15HTR1FDRD2 | |
| Oxalic Acid SCHEMBL7865005 | 0.77 | KDM4E (0.59) | KDM4ELMNAALOX15HTR1FDRD2 | |
| SCHEMBL11321052 | 0.77 | KDM4E (1.00) | KDM4ELMNAALOX15DRD2HTR1A | |
| Hydrochloric Acid SCHEMBL11325899 | 0.77 | KDM4E (1.00) | KDM4ELMNAALOX15DRD2HTR1A | |
| SCHEMBL7485434 | 0.76 | KDM4E (0.60) | KDM4ELMNAALOX15HTR1FDRD2 | |
| Phosphoric Acid SCHEMBL7868039 | 0.75 | HTR1D (0.38) | KDM4ELMNAALOX15HTR1FDRD2 | |
| SCHEMBL7870827 | 0.75 | KDM4E (0.37) | KDM4ELMNAALOX15HTR1FMAPT | |
| Phosphoric Acid SCHEMBL7870823 | 0.73 | HTR1F (0.39) | KDM4ELMNAALOX15HTR1F | |
| Phosphoric Acid SCHEMBL7859763 | 0.73 | HTR1F (0.42) | KDM4ELMNAALOX15HTR1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812826-A1 | 1H-indole and benzo(b)thiophene derivatives with 4-(1,2,3,6-tetra:hydro:pyridinyl)- and 4-piperidinyl-groups bound to the heterocyclic ring as inhibitors of serotonin reuptake | ELI LILLY AND COMPANY (US) | 1997-12-17 | — | — | EP | disclosed |