Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | DHODH | Q02127 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.46 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.46 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1307479 | 0.84 | MEN1 (0.54) | KMT2ADHODHNPC1RAB9AMEN1 | |
| SCHEMBL8798215 | 0.84 | DHODH (0.50) | KMT2AL3MBTL1HTTDHODHLMNA | |
| SCHEMBL18640723 | 0.82 | MEN1 (0.60) | KMT2AL3MBTL1POLBHTTDHODH | |
| SCHEMBL8800517 | 0.79 | KMT2A (0.67) | KMT2AL3MBTL1POLBHTTDHODH | |
| SCHEMBL10844635 | 0.79 | KMT2A (0.66) | KMT2AL3MBTL1POLBHTTLMNA | |
| SCHEMBL13789621 | 0.79 | DHODH (0.55) | KMT2AL3MBTL1HTTDHODHLMNA | |
| SCHEMBL27907868 | 0.78 | KMT2A (0.55) | KMT2AL3MBTL1HTTNPC1RAB9A | |
| SCHEMBL19595250 | 0.77 | RAB9A (0.48) | KMT2AL3MBTL1HTTGAANPC1 | |
| SCHEMBL8604699 | 0.76 | DHODH (0.64) | KMT2AL3MBTL1HTTDHODHLMNA | |
| SCHEMBL31439510 | 0.76 | DHODH (0.55) | KMT2AL3MBTL1HTTDHODHLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | disclosed |