Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 3/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797922 | 0.91 | HPGD (0.52) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8797917 | 0.91 | HPGD (0.52) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8797677 | 0.89 | CSNK2A2 (0.51) | HPGDCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL8796784 | 0.87 | MGAM (0.46) | HPGDCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL8798476 | 0.86 | GAA (0.41) | HPGDCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL8796699 | 0.84 | CSNK2A2 (0.51) | HPGDCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL8797746 | 0.84 | CSNK2A2 (0.43) | HPGDCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL8796662 | 0.83 | PSEN1 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8797031 | 0.83 | MGAM (0.45) | HPGDCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL8797670 | 0.80 | HPGD (0.52) | HPGDMAOAMAOBCISD1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787727-A1 | Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same | SS Pharmaceutical Co., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |