SCHEMBL8797746

SCHEMBL8797746

Cc1ccc2c(c1)OCN(CCOc1ccc(C=C3NC(=O)SC3=O)cc1)C2=O

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 1/20 0.43
CLK1 P49759 1/20 0.43
CSNK2B P67870 1/20 0.43
CSNK2A1 P68400 1/20 0.43
DYRK1A Q13627 1/20 0.43
DYRK2 Q92630 1/20 0.43
DYRK1B Q9Y463 1/20 0.43
HPGD P15428 8/20 0.42
PIM1 P11309 2/20 0.41
PIM2 Q9P1W9 2/20 0.41
HRH3 Q9Y5N1 1/20 0.39
MAOA P21397 2/20 0.38
MAOB P27338 2/20 0.38
CISD1 Q9NZ45 1/20 0.38
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8796699 0.91 CSNK2A2 (0.51) CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A
SCHEMBL8797738 0.91 HPGD (0.52) HPGDPIM1PIM2HRH3MAOA
SCHEMBL8797741 0.91 HPGD (0.52) HPGDPIM1PIM2HRH3MAOA
SCHEMBL8796784 0.87 MGAM (0.46) CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A
SCHEMBL8797677 0.86 CSNK2A2 (0.51) CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A
SCHEMBL8797928 0.84 PSEN1 (0.44) CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A
SCHEMBL8797091 0.83 ALDH1A1 (0.41) HPGDMAOB
SCHEMBL8797031 0.83 MGAM (0.45) CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A
SCHEMBL8796684 0.82 HPGD (0.52) HPGDPIM1PIM2HRH3MAOA
SCHEMBL8796691 0.82 HPGD (0.52) HPGDPIM1PIM2HRH3MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0787727-A1 Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same SS Pharmaceutical Co., Ltd. (JP) 1997-08-06 EP disclosed