Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 13/20 | 0.77 |
| ▸ | AVPR2 | P30518 | 11/20 | 0.77 |
| ▸ | AVPR1B | P47901 | 6/20 | 0.76 |
| ▸ | OXTR | P30559 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6990006 | 0.90 | AVPR1A (0.79) | AVPR1AAVPR2AVPR1BOXTR | |
| SCHEMBL8796878 | 0.89 | AVPR1A (0.67) | AVPR1AAVPR2AVPR1BOXTR | |
| SCHEMBL8797804 | 0.87 | AVPR1A (1.00) | AVPR1AAVPR2AVPR1BOXTR | |
| SCHEMBL6991947 | 0.87 | AVPR1A (0.65) | AVPR1AAVPR2AVPR1BOXTR | |
| SCHEMBL6989178 | 0.87 | AVPR2 (0.69) | AVPR1AAVPR2AVPR1BOXTR | |
| SCHEMBL6988392 | 0.87 | AVPR1A (0.64) | AVPR1AAVPR2AVPR1B | |
| SCHEMBL6989046 | 0.86 | AVPR1A (1.00) | AVPR1AAVPR2AVPR1BOXTR | |
| SCHEMBL6987073 | 0.85 | AVPR1A (0.80) | AVPR1AAVPR2AVPR1BOXTR | |
| SCHEMBL8797460 | 0.85 | AVPR1A (0.62) | AVPR1AAVPR2AVPR1BOXTR | |
| SCHEMBL8799494 | 0.83 | AVPR1A (0.65) | AVPR1AAVPR2AVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | disclosed |