SCHEMBL8798359

SCHEMBL8798359

CCC(CC)NC(=O)OCCCc1c[nH]cn1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 17/20 0.47
HRH4 Q9H3N8 5/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4376605 0.86 HRH3 (0.46) HRH3HRH4
SCHEMBL4383620 0.84 HRH3 (0.63) HRH3HRH4
SCHEMBL4384376 0.82 HRH3 (0.64) HRH3HRH4
SCHEMBL4390122 0.81 HRH3 (0.63) HRH3HRH4
SCHEMBL4379240 0.81 HRH3 (0.65) HRH3HRH4
SCHEMBL7994817 0.80 ACHE (0.47) HRH3HRH4
SCHEMBL4376053 0.79 HRH3 (0.49) HRH3HRH4
SCHEMBL5157531 0.78 NAAA (0.35) HRH3HRH4
SCHEMBL4383626 0.78 ACHE (0.53) HRH3
SCHEMBL4384700 0.78 HRH3 (0.39) HRH3HRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0760811-A1 IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H 3? (ANT)AGONISTS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 1997-03-12 EP disclosed