Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.43 |
| ▸ | HPGD | P15428 | 9/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SDHB | P21912 | 2/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14334477 | 0.75 | KDM4E (0.53) | SMN1; SMN2KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL10614056 | 0.74 | KDM4E (0.45) | SMN1; SMN2KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL11082771 | 0.74 | GAA (0.47) | SMN1; SMN2KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL6866430 | 0.73 | IDO1 (0.35) | — | |
| SCHEMBL11623789 | 0.72 | HPGD (0.43) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL27348070 | 0.72 | PTGS1 (0.37) | ALDH1A1KMT2ATP53L3MBTL1MAPT | |
| SCHEMBL649565 | 0.72 | HPGD (0.56) | KDM4EALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL11625133 | 0.70 | KIF11 (0.44) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL8797359 | 0.70 | GFER (0.50) | KDM4EHPGDNPC1RAB9A | |
| SCHEMBL2045079 | 0.70 | METAP1 (0.40) | RAB9AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772600-A1 | 1,2-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996003388-A1 | 1,2-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-02-08 | — | — | WO | disclosed |