Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TYMP | P19971 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 4/20 | 0.44 |
| ▸ | TNKS | O95271 | 2/20 | 0.42 |
| ▸ | WNT3A | P56704 | 2/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | COMT | P21964 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11623789 | 0.92 | HPGD (0.43) | GFERKDM4ENPC1POLBRAB9A | |
| SCHEMBL26093883 | 0.85 | KDM4E (0.44) | GFERKDM4ENPC1POLBRAB9A | |
| SCHEMBL11625133 | 0.85 | KIF11 (0.44) | GFERKDM4EKIF11MAPK13RAF1 | |
| SCHEMBL27731893 | 0.84 | NPBWR1 (0.44) | ATMTYMPTRPV1HPGDNPBWR1 | |
| SCHEMBL11626212 | 0.84 | KIF11 (0.42) | GFERKDM4ENPC1POLBRAB9A | |
| SCHEMBL3095172 | 0.84 | HPGD (0.38) | GFERKDM4ENPC1POLBRAB9A | |
| SCHEMBL27731900 | 0.84 | KDM4E (0.45) | KDM4ENPC1RAB9ATYMPMAPK13 | |
| SCHEMBL16661274 | 0.84 | KDM4E (0.45) | GFERKDM4ETYMPTNKSTNKS2 | |
| SCHEMBL649565 | 0.83 | HPGD (0.56) | KDM4EPOLBRAB9AKIF11TNKS | |
| SCHEMBL3468298 | 0.80 | HPGD (0.38) | GFERHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125360-A1 | HERBICIDAL IMIDAZOLE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2026-05-07 | — | — | US | disclosed |
| EP-4598913-A1 | HERBICIDAL IMIDAZOLE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2025-08-13 | — | — | EP | disclosed |
| CN-119968363-A | Herbicidal imidazole compounds | 先正达农作物保护股份公司 | 2025-05-09 | — | — | CN | disclosed |
| WO-2024074414-A1 | HERBICIDAL IMIDAZOLE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-04-11 | — | — | WO | disclosed |
| WO-2024074414-A1 | HERBICIDAL IMIDAZOLE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-04-11 | — | — | WO | disclosed |
| CN-101273040-B | Diazolylpyrazolopyrimidines as MGLUR2 antagonists | HOFFMANN LA ROCHE | 2011-11-09 | — | — | CN | disclosed |
| CN-101239981-B | Pyrazolo and imidazo-pyrimidine derivatives | HOFFMANN LA ROCHE | 2011-01-19 | — | — | CN | disclosed |
| CN-101180299-B | Ethynyl-pyrazolopyrimidine derivatives as MGLUR2 antagonists | HOFFMANN LA ROCHE | 2010-12-15 | — | — | CN | disclosed |
| CN-100522964-C | Pyrazolo and imidazo-pyrimidine derivatives | HOFFMANN LA ROCHE (CH) | 2009-08-05 | — | — | CN | disclosed |
| CN-101273040-A | Oxadiazolyl pyrazolopyrimidines as MGLUR2 antagonists | HOFFMANN LA ROCHE (CH) | 2008-09-24 | — | — | CN | disclosed |
| CN-101239981-A | Pyrazolo and imidazo-pyrimidine derivatives | HOFFMANN LA ROCHE (CH) | 2008-08-13 | — | — | CN | disclosed |
| CN-101180299-A | Ethynyl-pyrazolopyrimidine derivatives as MGLUR2 antagonists | HOFFMANN LA ROCHE (CH) | 2008-05-14 | — | — | CN | disclosed |
| CN-1890242-A | Pyrazolo and imidazo-pyrimidine derivatives | HOFFMANN LA ROCHE (CH) | 2007-01-03 | — | — | CN | disclosed |
| EP-0772600-A1 | 1,2-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996003388-A1 | 1,2-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125360-A1 | HERBICIDAL IMIDAZOLE COMPOUNDS | CBR3, CBR1, OSR1 | GFER 248/4885KDM4E 1064/4885NPC1 1270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.