Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PPIB | P23284 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12489932 | 0.84 | ATM (0.48) | ATMSIGMAR1L3MBTL1MAOBKDM4E | |
| SCHEMBL2783959 | 0.80 | MAPT (0.63) | ATMKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8800839 | 0.79 | MAPT (0.37) | L3MBTL1MAOBKDM4EALDH1A1MAPT | |
| SCHEMBL15346163 | 0.78 | ATM (0.48) | ATMSIGMAR1L3MBTL1MAOBKDM4E | |
| SCHEMBL8797759 | 0.77 | MAOB (0.42) | ATMMAOBKDM4EALDH1A1MAPT | |
| SCHEMBL2784597 | 0.77 | MAOB (0.59) | MAOBKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11105381 | 0.77 | ATM (0.42) | ATMSIGMAR1L3MBTL1MAOBKDM4E | |
| SCHEMBL8797874 | 0.75 | KDM4E (0.48) | ATMKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30065841 | 0.75 | ALDH1A1 (0.60) | ATMSIGMAR1MAOBKDM4EALDH1A1 | |
| SCHEMBL544297 | 0.75 | ALDH1A1 (0.60) | ATMSIGMAR1MAOBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514942-B1 | Novel benzopyran derivatives and processes for the preparation thereof | KOREA RES INST CHEM TECH (KR) | 1997-03-05 | — | — | EP | disclosed |
| US-5493029-A | USEFUL IN TREATING ASTHMA AND HYPERTENSION | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1996-02-20 | — | — | US | disclosed |
| EP-0514935-B1 | Novel benzopyran derivatives and processes for the preparation thereof | KOREA RES INST CHEM TECH (KR) | 1995-11-08 | — | — | EP | disclosed |
| US-5300511-A | Spiro-benzopyran derivatives and useful for treating asthma and hypertension | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1994-04-05 | — | — | US | disclosed |
| US-5236935-A | Hypotensive agents | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-08-17 | — | — | US | disclosed |
| EP-0514942-A1 | Novel benzopyran derivatives and processes for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-11-25 | — | — | EP | disclosed |
| EP-0514935-A1 | Novel benzopyran derivatives and processes for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-11-25 | — | — | EP | disclosed |