Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 15/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6604268 | 0.84 | MAOB (0.82) | MAOBALDH1A1KDM4EHPGDGAA | |
| SCHEMBL2786854 | 0.83 | MAOB (0.49) | MAOBALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL2784548 | 0.81 | MAOB (0.47) | MAOBALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL2784267 | 0.80 | MAOB (0.61) | MAOBALDH1A1KDM4EHPGDGAA | |
| SCHEMBL2783959 | 0.78 | MAPT (0.63) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL8797874 | 0.77 | KDM4E (0.48) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL8798562 | 0.77 | ATM (0.44) | MAOBALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL8800839 | 0.76 | MAPT (0.37) | MAOBALDH1A1KDM4EHPGDGAA | |
| SCHEMBL2494139 | 0.75 | MAOB (0.57) | MAOBALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL13339743 | 0.75 | ALDH1A1 (0.56) | MAOBALDH1A1KDM4EHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010128038-A1 | HYDROQUINONE DERIVATIVES | AXOGLIA THERAPEUTICS S.A. (LU) | 2010-11-11 | — | — | WO | disclosed |