Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 5/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798568 | 0.93 | ADRA1A (0.44) | ADRA1AADRA1DHTR3AADRA2AADRA2B | |
| SCHEMBL8543708 | 0.87 | ADRA1A (0.43) | ADRA1AADRA1DHTR3AADRA2AADRA2B | |
| SCHEMBL8540944 | 0.82 | HTR3A (0.43) | ADRA1AADRA1DHTR3AADRA2AADRA2B | |
| SCHEMBL8542709 | 0.81 | HTR3A (0.41) | ADRA1AADRA1DHTR3AADRA2AADRA2B | |
| SCHEMBL8543700 | 0.80 | ADRA1A (0.36) | ADRA1AHTR3AADRA2AADRA2BADRA2C | |
| SCHEMBL8540950 | 0.79 | ADRA1A (0.55) | ADRA1AADRA1DHTR3AADRA2AADRA2B | |
| SCHEMBL8544447 | 0.79 | HTR3A (0.45) | ADRA1AADRA1DHTR3AADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL8540932 | 0.78 | ADRA1A (0.54) | ADRA1AADRA1DHTR3AADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL8538937 | 0.78 | HTR3A (0.44) | ADRA1AADRA1DHTR3AADRA2AADRA2B | |
| SCHEMBL8479745 | 0.78 | ADRA1A (0.48) | ADRA1AADRA1DHTR3AADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810214-A1 | PROCESS FOR PRODUCING INDOLINE COMPOUNDS AND INTERMEDIATES FOR THE PRODUCTION OF THE SAME | TOKYO TANABE COMPANY LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |