Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 7/20 | 0.76 |
| ▸ | PARN | O95453 | 1/20 | 0.76 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13861874 | 0.91 | CNOT7 (0.70) | CNOT7PARNBRD4POLBHIF1A | |
| SCHEMBL9391031 | 0.87 | CNOT7 (0.59) | CNOT7PARNBRD4POLBHIF1A | |
| SCHEMBL4420441 | 0.86 | CNOT7 (0.72) | CNOT7PARNBRD4POLBHIF1A | |
| SCHEMBL16058255 | 0.81 | CNOT7 (0.58) | CNOT7PARNBRD4POLBHIF1A | |
| SCHEMBL554897 | 0.78 | CNOT7 (0.61) | CNOT7PARNBRD4ALDH1A1SMN1; SMN2 | |
| SCHEMBL2984842 | 0.77 | CNOT7 (0.54) | CNOT7PARNBRD4ALDH1A1ADORA2B | |
| SCHEMBL556233 | 0.77 | BRD4 (0.82) | CNOT7PARNBRD4POLBKDM4E | |
| SCHEMBL2993196 | 0.76 | CNOT7 (0.53) | CNOT7PARNBRD4ALDH1A1ADORA2B | |
| SCHEMBL18024115 | 0.76 | GRIN1 (0.52) | CNOT7PARNRXFP1KMT2A | |
| SCHEMBL1945875 | 0.75 | KMT2A (0.69) | CNOT7POLBHIF1AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538332-B1 | POLYCYCLIC GUANINE DERIVATIVES | SCHERING CORP (US) | 1997-07-23 | — | — | EP | disclosed |
| US-5393755-A | Hypotensive agents, enzyme inhibitors | SCHERING CORPORATION (US) | 1995-02-28 | — | — | US | disclosed |