Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798892 | 0.90 | ALDH1A1 (0.32) | ALDH1A1POLBMAPT | |
| SCHEMBL8801073 | 0.75 | CA12 (0.42) | ALDH1A1POLBMAPT | |
| SCHEMBL30661865 | 0.70 | ALDH1A1 (0.37) | ALDH1A1POLBMAPT | |
| SCHEMBL1218874 | 0.70 | ALDH1A1 (0.37) | ALDH1A1POLBMAPT | |
| SCHEMBL10678902 | 0.70 | SMN1; SMN2 (0.41) | ALDH1A1POLBMAPT | |
| SCHEMBL8798369 | 0.70 | MEN1 (0.38) | ALDH1A1POLBMAPT | |
| SCHEMBL8799000 | 0.70 | CA12 (0.35) | — | |
| SCHEMBL8973731 | 0.68 | POLB (0.36) | ALDH1A1POLBMAPT | |
| SCHEMBL8798971 | 0.68 | ALDH1A1 (0.32) | ALDH1A1POLBMAPT | |
| SCHEMBL10681934 | 0.68 | RXFP1 (0.48) | ALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355827-B1 | Hydantoin derivatives | MOCHIDA PHARM CO LTD (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-RE35279-E | ALDOSE REDUCTASE INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1996-06-18 | — | — | US | disclosed |
| US-5202339-A | Hypoglycemic, hypolipedemic agents | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| US-5004751-A | Antidiabetic agents; aldoe reductase inhibitors | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1991-04-02 | — | — | US | disclosed |
| WO-1990002126-A1 | HYDANTOIN DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-03-08 | — | — | WO | disclosed |
| EP-0355827-A2 | Hydantoin derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |