SCHEMBL8798995

SCHEMBL8798995

CCCCCCCCCCCCCCCCNS(=O)(=O)c1cccc(C(N)=O)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.55
MAPK1 P28482 2/20 0.55
HTT P42858 1/20 0.55
CYP2C19 P33261 1/20 0.52
EPHX2 P34913 1/20 0.52
ALDH1A1 P00352 5/20 0.49
AKR1C3 P42330 4/20 0.49
KDM4E B2RXH2 1/20 0.49
PKM P14618 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
PDK1 Q15118 1/20 0.48
PDK2 Q15119 1/20 0.48
PDK3 Q15120 1/20 0.48
PDK4 Q16654 1/20 0.48
MEP1B Q16820 1/20 0.48
TBXA2R P21731 1/20 0.48
TDP1 Q9NUW8 2/20 0.47
KMT2A Q03164 1/20 0.47
CA12 O43570 1/20 0.47
CA9 Q16790 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17713153 0.99 CYP2C19 (0.53) LMNAMAPK1HTTCYP2C19EPHX2
SCHEMBL2859691 0.95 CYP2C19 (0.55) LMNAMAPK1HTTCYP2C19ALDH1A1
SCHEMBL8798988 0.87 CYP2C19 (0.52) LMNAMAPK1HTTCYP2C19EPHX2
SCHEMBL11668172 0.86 ALDH1A1 (0.63) LMNAMAPK1HTTCYP2C19EPHX2
SCHEMBL2851017 0.84 BRAF (0.52) MAPK1CYP2C19ALDH1A1AKR1C3SMN1; SMN2
SCHEMBL2850555 0.83 LMNA (0.53) LMNAMAPK1HTTCYP2C19ALDH1A1
SCHEMBL28091838 0.83 CYP2C19 (0.53) MAPK1HTTCYP2C19ALDH1A1AKR1C3
SCHEMBL5034887 0.82 CYP2C19 (0.76) MAPK1HTTCYP2C19ALDH1A1AKR1C3
SCHEMBL6151749 0.81 PRMT1 (0.59) LMNAMAPK1HTTCYP2C19EPHX2
SCHEMBL2848724 0.81 ALDH1A1 (0.60) MAPK1CYP2C19ALDH1A1AKR1C3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0571959-B1 Photographic coupler and silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1997-04-09 EP disclosed
US-5532377-A MAGENTA COUPLERS FOR COLOR PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1996-07-02 US disclosed
EP-0688774-A1 Compounds for preparing a photographic magenta coupler FUJI PHOTO FILM CO., LTD. (JP) 1995-12-27 EP disclosed
US-5451501-A Light sensitive element with magenta coupler on support FUJI PHOTO FILM CO., LTD. (JP) 1995-09-19 US disclosed
EP-0571959-A2 Photographic coupler and silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1993-12-01 EP disclosed