Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSD | A5PKW4 | 8/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.40 |
| ▸ | GYS1 | P13807 | 1/20 | 0.40 |
| ▸ | ARF6 | P62330 | 3/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798543 | 0.80 | PSD (0.40) | PSDKCNQ3KCNQ2GYS1ARF6 | |
| SCHEMBL8798414 | 0.76 | PSD (0.34) | PSDKCNQ3KCNQ2GYS1CYP1A2 | |
| SCHEMBL3123053 | 0.74 | KDM4E (0.48) | PSDKCNQ3KCNQ2CYP1A2CYP2C19 | |
| SCHEMBL9015062 | 0.73 | KDM4E (0.48) | PSDKCNQ3KCNQ2GYS1ARF6 | |
| SCHEMBL8798325 | 0.72 | PSD (0.34) | PSDKCNQ3KCNQ2GYS1CYP1A2 | |
| SCHEMBL13858869 | 0.71 | ALDH1A1 (0.46) | PSD | |
| SCHEMBL8662105 | 0.71 | PSD (0.34) | PSDKCNQ3KCNQ2GYS1CYP1A2 | |
| SCHEMBL116957 | 0.71 | ALDH1A1 (0.46) | PSD | |
| SCHEMBL7786390 | 0.70 | TUBB4A (0.36) | PSDCYP1A2CYP2C19RECQL | |
| SCHEMBL9446485 | 0.69 | GRM5 (0.47) | PSDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481182-B1 | Bis- and tris(trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID CO (US) | 1997-01-29 | — | — | EP | claimed |
| US-5157047-A | Miticides | AMERICAN CYANAMID COMPANY (US) | 1992-10-20 | — | — | US | claimed |
| EP-0481182-A1 | Bis- and tris(trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-22 | — | — | EP | claimed |
| EP-0481182-B1 | Bis- and tris(trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID CO (US) | 1997-01-29 | — | — | EP | disclosed |
| US-5281719-A | Reacting a methyl N-((trimethylsilyl)methyl)thiobenzimidate with 2,3-dichloro-hexafluorobutene to give a 2-aryl-3,4-bis-(trifluoromethyl)pyrrole and reacting this with a halogenating compound | AMERICAN CYANAMID COMPANY (US) | 1994-01-25 | — | — | US | disclosed |
| US-5229524-A | Bis-and tris (trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1993-07-20 | — | — | US | disclosed |
| US-5157047-A | Miticides | AMERICAN CYANAMID COMPANY (US) | 1992-10-20 | — | — | US | disclosed |
| EP-0481182-A1 | Bis- and tris(trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-22 | — | — | EP | disclosed |