Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.77 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | CA12 | O43570 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | CA3 | P07451 | 1/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.60 |
| ▸ | CA4 | P22748 | 1/20 | 0.60 |
| ▸ | CA6 | P23280 | 1/20 | 0.60 |
| ▸ | CA5A | P35218 | 1/20 | 0.60 |
| ▸ | CA7 | P43166 | 1/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800213 | 0.87 | PDE3B (1.00) | PDE3BPDE3AALDH1A1HPGDCA12 | |
| SCHEMBL2474491 | 0.77 | PDE3B (0.50) | PDE3BPDE3AALDH1A1HPGDCA12 | |
| Herniarin SCHEMBL17629468 | 0.75 | CA12 (1.00) | ALDH1A1HPGDCA12CA1CA9 | |
| Herniarin SCHEMBL61221 | 0.75 | CA12 (1.00) | ALDH1A1HPGDCA12CA1CA9 | |
| Herniarin SCHEMBL29437733 | 0.75 | CA12 (1.00) | ALDH1A1HPGDCA12CA1CA9 | |
| Herniarin SCHEMBL17113785 | 0.74 | CA12 (0.96) | ALDH1A1HPGDCA12CA1CA9 | |
| SCHEMBL10926839 | 0.74 | CA9 (0.56) | PDE3BPDE3AALDH1A1HPGDCA12 | |
| SCHEMBL8787024 | 0.72 | PDE3B (0.45) | PDE3BPDE3AALDH1A1HPGDCA12 | |
| SCHEMBL29489333 | 0.72 | ALDH1A1 (0.49) | PDE3BPDE3AALDH1A1HPGDCA12 | |
| SCHEMBL4859239 | 0.72 | ALDH1A1 (0.49) | PDE3BPDE3AALDH1A1HPGDCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506539-B1 | Heterocyclic alkylamides, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1997-05-02 | — | — | EP | disclosed |
| US-5386034-A | Treatment of sleeping, psychological and nervous system disorders; anxiolytic agents, ovulation regulators | ADIR ET COMPAGNIE (FR) | 1995-01-31 | — | — | US | disclosed |
| US-5326775-A | Treating sleep disorders | ADIR ET COMPAGNIE (FR) | 1994-07-05 | — | — | US | disclosed |
| US-5322843-A | Treating sleep disorders | ADIR ET COMPAGNIE (FR) | 1994-06-21 | — | — | US | disclosed |
| US-5322849-A | Treating sleep disorders | ADIR ET COMPAGNIE (FR) | 1994-06-21 | — | — | US | disclosed |
| US-5300507-A | Treating sleep disorders | ADIR ET COMPAGNIE (FR) | 1994-04-05 | — | — | US | disclosed |
| US-5240919-A | Treating sleep disorders | ADIR ET COMPAGNIE (FR) | 1993-08-31 | — | — | US | disclosed |
| EP-0506539-A1 | Heterocyclic alkylamides, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-09-30 | — | — | EP | disclosed |