Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.66 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26032569 | 0.84 | BPTF (0.65) | BPTFHSD11B1TSHRGRM1EPHX1 | |
| SCHEMBL8801573 | 0.82 | BPTF (0.46) | BPTFHSD11B1TSHRGRM1EPHX1 | |
| SCHEMBL29201838 | 0.76 | BPTF (0.68) | BPTFHSD11B1TSHRGRM1EPHX1 | |
| SCHEMBL8749014 | 0.75 | BPTF (0.72) | BPTFHSD11B1TSHRALDH1A1KDM4E | |
| SCHEMBL12204818 | 0.75 | BPTF (0.72) | BPTFHSD11B1TSHRALDH1A1KDM4E | |
| SCHEMBL31119839 | 0.75 | BPTF (0.72) | BPTFHSD11B1TSHRGRM1EPHX1 | |
| SCHEMBL26032675 | 0.75 | BPTF (0.53) | BPTFHSD11B1TSHRGRM1EPHX1 | |
| SCHEMBL640879 | 0.74 | BPTF (0.70) | BPTFHSD11B1TSHRGRM1EPHX1 | |
| SCHEMBL8748855 | 0.74 | BPTF (0.70) | BPTFHSD11B1TSHRALDH1A1KDM4E | |
| SCHEMBL2529216 | 0.74 | BPTF (0.70) | BPTFHSD11B1TSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650406-A | ANTISCHIZOPHRENIC AGENT | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-07-22 | — | — | US | disclosed |
| EP-0757040-A1 | ADAMANTANE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1997-02-05 | — | — | EP | disclosed |