Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.68 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.45 |
| ▸ | DPP4 | P27487 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31119839 | 0.80 | BPTF (0.72) | BPTFHSD11B1TSHREPHX1EPHX2 | |
| SCHEMBL29201782 | 0.78 | BPTF (0.55) | BPTFHSD11B1TSHREPHX1EPHX2 | |
| SCHEMBL2790543 | 0.77 | HSD11B1 (0.62) | HSD11B1TSHRALDH1A1KDM4ELMNA | |
| SCHEMBL12204818 | 0.77 | BPTF (0.72) | BPTFHSD11B1TSHRALDH1A1KDM4E | |
| SCHEMBL8749014 | 0.77 | BPTF (0.72) | BPTFHSD11B1TSHRALDH1A1KDM4E | |
| SCHEMBL1713095 | 0.77 | ALOX5 (0.44) | EPHX2ALDH1A1 | |
| SCHEMBL8799134 | 0.76 | BPTF (0.66) | BPTFHSD11B1TSHREPHX1EPHX2 | |
| SCHEMBL640879 | 0.75 | BPTF (0.70) | BPTFHSD11B1TSHREPHX1DPP4 | |
| SCHEMBL8748855 | 0.75 | BPTF (0.70) | BPTFHSD11B1TSHRALDH1A1HPGD | |
| SCHEMBL8749192 | 0.75 | BPTF (0.70) | BPTFHSD11B1TSHRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447466-A | Oxazole compound and preparation method and application thereof | 中国科学院上海药物研究所 | 2024-01-26 | — | — | CN | disclosed |