Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799134 | 0.82 | BPTF (0.66) | BPTFHSD11B1GRM1TSHREPHX1 | |
| SCHEMBL503339 | 0.76 | POLB (0.64) | GAALMNATSHRPOLB | |
| SCHEMBL7588383 | 0.76 | POLB (0.64) | GAALMNATSHRPOLB | |
| SCHEMBL10532442 | 0.76 | GAA (0.51) | GAATSHRPOLB | |
| Hydrochloric Acid SCHEMBL10532450 | 0.74 | POLB (0.62) | GAALMNATSHRPOLB | |
| SCHEMBL8544600 | 0.72 | GAA (0.47) | GAATSHRPOLB | |
| SCHEMBL8799246 | 0.71 | GRIN2D (0.38) | HTTTSHR | |
| SCHEMBL17067654 | 0.70 | ALDH1A1 (0.47) | GAATSHRPOLB | |
| SCHEMBL19909619 | 0.70 | BPTF (0.46) | BPTFHSD11B1GAALMNAHTT | |
| SCHEMBL26032569 | 0.69 | BPTF (0.65) | BPTFHSD11B1GRM1TSHREPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650406-A | ANTISCHIZOPHRENIC AGENT | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-07-22 | — | — | US | disclosed |
| EP-0757040-A1 | ADAMANTANE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1997-02-05 | — | — | EP | disclosed |