Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817261 | 0.81 | GPR35 (0.47) | GPR35ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7827473 | 0.79 | TDP1 (0.44) | GPR35ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7829809 | 0.79 | TDP1 (0.44) | GPR35ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8344224 | 0.76 | TDP1 (0.42) | GPR35ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7826124 | 0.76 | ALDH1A1 (0.60) | GPR35ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7816604 | 0.74 | GPR35 (0.43) | GPR35ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7826454 | 0.73 | GPR35 (0.44) | GPR35ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7826452 | 0.73 | GPR35 (0.44) | GPR35ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28490813 | 0.72 | GPR35 (0.41) | GPR35ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7827949 | 0.72 | TDP1 (0.46) | GPR35ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757682-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |