Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 5/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9121368 | 0.86 | MEN1 (0.43) | MEN1KMT2ASLC6A3KDM4CADORA3 | |
| SCHEMBL8463856 | 0.85 | CYP4F2 (0.41) | MEN1KMT2ASLC6A3ADORA3MGLL | |
| SCHEMBL9120024 | 0.85 | CYP4F2 (0.44) | MEN1KMT2ASLC6A3ADORA3MGLL | |
| SCHEMBL9121608 | 0.85 | CYP4F2 (0.44) | MEN1KMT2ASLC6A3ADORA3MGLL | |
| SCHEMBL9120971 | 0.85 | CYP4F2 (0.44) | MEN1KMT2ASLC6A3ADORA3MGLL | |
| SCHEMBL8799817 | 0.85 | MEN1 (0.43) | MEN1KMT2ASLC6A3KDM4CADORA3 | |
| SCHEMBL8799592 | 0.84 | MEN1 (0.42) | MEN1KMT2ASLC6A3KDM4CADORA3 | |
| SCHEMBL8799956 | 0.84 | MEN1 (0.42) | MEN1KMT2ASLC6A3KDM4CADORA3 | |
| SCHEMBL9120035 | 0.84 | MEN1 (0.42) | MEN1KMT2ASLC6A3KDM4CADORA3 | |
| SCHEMBL9120025 | 0.84 | MEN1 (0.41) | MEN1KMT2ASLC6A3KDM4CADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755381-A1 | SUBSTITUTED PYRIDINE LEUKOTRIENE B 4 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-01-29 | — | — | EP | disclosed |