Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9121608 | 1.00 | CYP4F2 (0.44) | CYP4F2CYP4A11MEN1KMT2AMGLL | |
| SCHEMBL9120024 | 1.00 | CYP4F2 (0.44) | CYP4F2CYP4A11MEN1KMT2AMGLL | |
| SCHEMBL8463856 | 0.98 | CYP4F2 (0.41) | CYP4F2CYP4A11MEN1KMT2AMGLL | |
| SCHEMBL9121368 | 0.94 | MEN1 (0.43) | CYP4F2CYP4A11MEN1KMT2AMGLL | |
| SCHEMBL9120035 | 0.87 | MEN1 (0.42) | MEN1KMT2AMGLLSLC6A3ADORA3 | |
| SCHEMBL8799817 | 0.86 | MEN1 (0.43) | MEN1KMT2AMGLLSLC6A3ADORA3 | |
| SCHEMBL8799956 | 0.86 | MEN1 (0.42) | MEN1KMT2AMGLLSLC6A3ADORA3 | |
| SCHEMBL8799592 | 0.86 | MEN1 (0.42) | MEN1KMT2ASLC6A3SMN1; SMN2ADORA3 | |
| Methane SCHEMBL8799260 | 0.85 | MEN1 (0.40) | MEN1KMT2AMGLLSLC6A3CYP1A2 | |
| SCHEMBL9120025 | 0.85 | MEN1 (0.41) | MEN1KMT2AMGLLSLC6A3ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434186-A | Antiinflammatory agents | HOFFMANN-LA ROCHE INC. (US) | 1995-07-18 | — | — | US | disclosed |
| US-5273999-A | A 4-keto-boroalkyleneoxychroman or 2,3-dihydrobenzofuran derivative | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |
| EP-0531823-A1 | Bicyclic carboxylic acid derivatives as anti-inflammatory agents | F. HOFFMANN-LA ROCHE AG (CH) | 1993-03-17 | — | — | EP | disclosed |