Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9121368 | 0.88 | MEN1 (0.43) | MEN1KMT2ASLC6A3ADORA3KDM4C | |
| SCHEMBL8799817 | 0.87 | MEN1 (0.43) | MEN1KMT2ASLC6A3ADORA3HPGD | |
| SCHEMBL8799956 | 0.86 | MEN1 (0.42) | MEN1KMT2ASLC6A3ADORA3HPGD | |
| SCHEMBL9120035 | 0.86 | MEN1 (0.42) | MEN1KMT2ASLC6A3ADORA3HPGD | |
| SCHEMBL9120024 | 0.86 | CYP4F2 (0.44) | MEN1KMT2ASLC6A3ADORA3SMN1; SMN2 | |
| SCHEMBL9121608 | 0.86 | CYP4F2 (0.44) | MEN1KMT2ASLC6A3ADORA3SMN1; SMN2 | |
| SCHEMBL9120025 | 0.86 | MEN1 (0.41) | MEN1KMT2ASLC6A3ADORA3HPGD | |
| SCHEMBL8463856 | 0.86 | CYP4F2 (0.41) | MEN1KMT2ASLC6A3ADORA3SMN1; SMN2 | |
| SCHEMBL9120971 | 0.86 | CYP4F2 (0.44) | MEN1KMT2ASLC6A3ADORA3SMN1; SMN2 | |
| Methane SCHEMBL8799260 | 0.84 | MEN1 (0.40) | MEN1KMT2ASLC6A3ALDH1A1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755381-A1 | SUBSTITUTED PYRIDINE LEUKOTRIENE B 4 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028386-A1 | SUBSTITUTED PYRIDINE LEUKOTRIENE B4 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1995-10-26 | — | — | WO | disclosed |