Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.62 |
| ▸ | CES1 | P23141 | 4/20 | 0.62 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.59 |
| ▸ | PPARG | P37231 | 7/20 | 0.59 |
| ▸ | PPARD | Q03181 | 7/20 | 0.59 |
| ▸ | PPARA | Q07869 | 7/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 5/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TLR2 | O60603 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | FABP4 | P15090 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.59 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | PDE4A | P27815 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2770033 | 1.00 | CES2 (0.62) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL8364614 | 1.00 | CES2 (0.62) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL368595 | 1.00 | — | — | |
| SCHEMBL8368438 | 1.00 | CES2 (0.62) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL5179381 | 1.00 | CES2 (0.62) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL8367953 | 1.00 | CES2 (0.62) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL8367955 | 1.00 | CES2 (0.62) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL583038 | 1.00 | CES2 (0.62) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL543736 | 1.00 | CES2 (0.62) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL8364543 | 1.00 | CES2 (0.62) | CES2CES1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170335037-A1 | VULCANIZABLE COMPOSITIONS CONTAINING EPOXY GROUP-CONTAINING ETHYLENE-VINYL ACETATE COPOLYMERS | ARLANXEO DEUTSCHLAND GMBH (DE) | 2017-11-23 | — | — | US | disclosed |
| US-8933195-B2 | Histone deacetylase inhibitors and synthetic method thereof and use thereof in manufacture of medicaments | NANJING YOKO BIOMEDICAL R & D LTD. (CN) | 2015-01-13 | — | — | US | disclosed |
| US-8933195-B2 | Histone deacetylase inhibitors and synthetic method thereof and use thereof in manufacture of medicaments | NANJING YOKO BIOMEDICAL R & D LTD. (CN) | 2015-01-13 | — | — | US | disclosed |
| US-20140243501-A1 | HISTONE DEACETYLASE INHIBITORS AND SYNTHETIC METHOD THEREOF AND USE THEREOF IN MANUFACTURE OF MEDICAMENTS | NANJING YOKO BIOMEDICAL R & D LTD. [CN/CN] (CN) | 2014-08-28 | — | — | US | disclosed |
| US-20140243501-A1 | HISTONE DEACETYLASE INHIBITORS AND SYNTHETIC METHOD THEREOF AND USE THEREOF IN MANUFACTURE OF MEDICAMENTS | NANJING YOKO BIOMEDICAL R & D LTD. [CN/CN] (CN) | 2014-08-28 | — | — | US | disclosed |
| WO-2013071715-A1 | HISTONE DEACETYLASE INHIBITORS AND SYNTHETIC METHOD THEREOF AND USE THEREOF IN MANUFACTURE OF MEDICAMENTS | 南京优科生物医药研究有限公司 (CN) | 2013-05-23 | — | — | WO | disclosed |
| US-5650430-A | Radicicol derivatives, their preparation and their anti-tumor activity | SANKYO COMPANY, LIMITED (JP) | 1997-07-22 | — | — | US | disclosed |
| EP-0460950-B1 | Radicicol derivatives, their preparation and their anti-tumour activity | SANKYO CO (JP) | 1997-03-05 | — | — | EP | disclosed |
| US-5597846-A | ESTERS OF RADICICOL | SANKYO COMPANY, LIMITED (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0316934-B1 | MURAMYL PEPTIDE DERIVATIVES AND USE THEREOF | Hasegawa, Akira (JP) | 1993-08-18 | — | — | EP | disclosed |
| WO-1991018905-A1 | RADICICOL DERIVATIVES, THEIR PREPARATION AND THEIR ANTI-TUMOR ACTIVITY | SANKYO COMPANY LIMITED (JP) | 1991-12-12 | — | — | WO | disclosed |
| EP-0460950-A1 | Radicicol derivatives, their preparation and their anti-tumour activity | Sankyo Company Limited (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-4895835-A | IMMUNOMODULATORS | NISSHIN OIL MILLS, LTD. (JP) | 1990-01-23 | — | — | US | disclosed |
| EP-0319316-A2 | Griseolic acid monoesters, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1989-06-07 | — | — | EP | disclosed |
| EP-0316934-A2 | Muramyl peptide derivatives and use thereof | Hasegawa, Akira (JP) | 1989-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243501-A1 | HISTONE DEACETYLASE INHIBITORS AND SYNTHETIC METHOD THEREOF AND USE THEREOF IN MANUFACTURE OF MEDICAMENTS | HDAC1, HDAC11, HDAC2 | CES2 1320/4885CES1 499/4885GPR84 1314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.