Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.62 |
| ▸ | CES1 | P23141 | 4/20 | 0.62 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.59 |
| ▸ | PPARG | P37231 | 7/20 | 0.59 |
| ▸ | PPARD | Q03181 | 7/20 | 0.59 |
| ▸ | PPARA | Q07869 | 7/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 5/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TLR2 | O60603 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | FABP4 | P15090 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.59 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | PDE4A | P27815 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8364614 | 1.00 | CES2 (0.62) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL368595 | 1.00 | — | — | |
| SCHEMBL8368438 | 1.00 | CES2 (0.62) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL5179381 | 1.00 | CES2 (0.62) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL8367953 | 1.00 | CES2 (0.62) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL8367955 | 1.00 | CES2 (0.62) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL583038 | 1.00 | CES2 (0.62) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL543736 | 1.00 | CES2 (0.62) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL8799322 | 1.00 | CES2 (0.62) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL8364543 | 1.00 | CES2 (0.62) | CES2CES1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0401193-B1 | Rubber compositions having improved processability | MONSANTO EUROPE SA (BE) | 1996-09-18 | — | — | EP | claimed |
| US-5023289-A | Alkylthioalkanoic acid flow control agent | MONSANTO EUROPE, S.A. (BE) | 1991-06-11 | — | — | US | claimed |
| EP-0401193-A1 | Rubber compositions having improved processability | MONSANTO EUROPE S.A./N.V. (BE) | 1990-12-05 | — | — | EP | claimed |
| US-4559153-A | MINERAL OR SYNTHETIC OIL, ALKYLTHIOHYDROCARBYL CARBOXYLIC ACID ANDVEGETABLE OR ANIMAL OIL; COLD ROLLING OF STEEL | PHILLIPS PETROLEUM COMPANY (US) | 1985-12-17 | — | — | US | claimed |
| EP-0142078-A1 | Metal working lubricant | PHILLIPS PETROLEUM COMPANY (US) | 1985-05-22 | — | — | EP | claimed |
| JP-3095240-A | — | — | None | — | — | JP | disclosed |
| US-9795586-B2 | HNF4-α antagonist and use thereof | NATIONAL CANCER CENTER (KR) | 2017-10-24 | — | — | US | disclosed |
| US-9795586-B2 | HNF4-α antagonist and use thereof | NATIONAL CANCER CENTER (KR) | 2017-10-24 | — | — | US | disclosed |
| US-20170189371-A1 | HNF4-alpha ANTAGONIST AND USE THEREOF | NATIONAL CANCER CENTER (KR) | 2017-07-06 | — | — | US | disclosed |
| US-20170189371-A1 | HNF4-alpha ANTAGONIST AND USE THEREOF | NATIONAL CANCER CENTER (KR) | 2017-07-06 | — | — | US | disclosed |
| CN-103665170-A | Peptide therapeutic conjugates and uses thereof | ANGIOCHEM INC | 2014-03-26 | — | — | CN | disclosed |
| CN-102348723-A | Peptide therapeutic agent conjugates and uses thereof | ANGIOCHEM INC | 2012-02-08 | — | — | CN | disclosed |
| EP-0250087-A1 | Pentaerythritol co-esters | MALLINCKRODT, INC. (US) | 1987-12-23 | — | — | EP | disclosed |
| EP-0240212-A2 | Preparation of highly pure alpha-methylstyrene polymer | THE DOW CHEMICAL COMPANY (US) | 1987-10-07 | — | — | EP | disclosed |
| EP-0234512-A2 | Crystaline block copolymer and process for producing the same | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1987-09-02 | — | — | EP | disclosed |
| US-4559153-A | MINERAL OR SYNTHETIC OIL, ALKYLTHIOHYDROCARBYL CARBOXYLIC ACID ANDVEGETABLE OR ANIMAL OIL; COLD ROLLING OF STEEL | PHILLIPS PETROLEUM COMPANY (US) | 1985-12-17 | — | — | US | disclosed |
| US-4559153-A | MINERAL OR SYNTHETIC OIL, ALKYLTHIOHYDROCARBYL CARBOXYLIC ACID ANDVEGETABLE OR ANIMAL OIL; COLD ROLLING OF STEEL | PHILLIPS PETROLEUM COMPANY (US) | 1985-12-17 | — | — | US | disclosed |
| EP-0142078-A1 | Metal working lubricant | PHILLIPS PETROLEUM COMPANY (US) | 1985-05-22 | — | — | EP | disclosed |
| EP-0142078-A1 | Metal working lubricant | PHILLIPS PETROLEUM COMPANY (US) | 1985-05-22 | — | — | EP | disclosed |
| EP-0086757-A1 | Derivatives of alpha or beta-mercaptopropionylamidoacetic acids, processes for their preparation and the therapeutic compositions which include them as active principles | Farmatis S.r.l. (IT) | 1983-08-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170189371-A1 | HNF4-alpha ANTAGONIST AND USE THEREOF | HNF4A, TCF4, WNT3A | CES2 4714/4885CES1 1902/4885GPR84 126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.