Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | PNP | P00491 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6357934 | 0.82 | PNP (0.41) | ALDH1A1SMN1; SMN2HPGDPNP | |
| SCHEMBL7113260 | 0.78 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2HPGDPNP | |
| SCHEMBL6843151 | 0.77 | SMN1; SMN2 (0.57) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL2778421 | 0.75 | KMT2A (0.46) | SMN1; SMN2HPGD | |
| SCHEMBL6357813 | 0.74 | PDE9A (0.44) | SMN1; SMN2HPGDPNP | |
| SCHEMBL6358364 | 0.73 | KMT2A (0.41) | ALDH1A1SMN1; SMN2HPGDPNP | |
| SCHEMBL6843150 | 0.73 | SMN1; SMN2 (0.57) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7775171 | 0.71 | HPGD (0.72) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL2952786 | 0.70 | BRD4 (0.59) | ALDH1A1HPGD | |
| SCHEMBL5789121 | 0.69 | KDM4E (0.55) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775142-A1 | SUBSTITUTED O6 -BENZYLGUANINES AND 6(4)-BENZYLOXYPYRIMIDINES | THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, Department of Health and Human Services (US) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996004281-A1 | SUBSTITUTED O6-BENZYLGUANINES AND 6(4)-BENZYLOXYPYRIMIDINES | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-02-15 | — | — | WO | disclosed |