Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6843150 | 0.79 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1HPGDRAB9ALMNA | |
| SCHEMBL8799469 | 0.77 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7113260 | 0.76 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1HPGDMEN1LMNA | |
| SCHEMBL6843154 | 0.74 | CLPP (0.45) | SMN1; SMN2HPGDCYP3A4CYP2C9PKM | |
| SCHEMBL7775171 | 0.71 | HPGD (0.72) | SMN1; SMN2ALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL21011260 | 0.66 | PDE9A (0.53) | — | |
| SCHEMBL28277006 | 0.66 | KDM4E (0.63) | SMN1; SMN2ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL7974022 | 0.66 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6356976 | 0.66 | PNP (0.70) | SMN1; SMN2HPGDPKMRAB9AMEN1 | |
| SCHEMBL8574273 | 0.65 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1HPGDPKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040122228-A1 | New purine derivatives, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122228-A1 | New purine derivatives, the preparation thereof and their use as pharmaceutical compositions | DPP4, DPP7, DPP3 | SMN1; SMN2 1872/4885ALDH1A1 241/4885HPGD 1769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.