Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 19/20 | 0.79 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.79 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8827882 | 0.99 | ALOX5 (0.80) | ALOX5HDAC6ALOX5AP | |
| SCHEMBL9124326 | 0.99 | ALOX5 (0.80) | ALOX5HDAC6ALOX5AP | |
| SCHEMBL9431826 | 0.99 | ALOX5 (0.80) | ALOX5HDAC6ALOX5AP | |
| SCHEMBL8827857 | 0.99 | ALOX5 (0.80) | ALOX5HDAC6ALOX5AP | |
| SCHEMBL9430158 | 0.99 | ALOX5 (0.80) | ALOX5HDAC6ALOX5AP | |
| SCHEMBL10423746 | 0.91 | ALOX5 (0.72) | ALOX5HDAC6ALOX5AP | |
| SCHEMBL27629358 | 0.91 | ALOX5 (0.78) | ALOX5HDAC6 | |
| SCHEMBL26838881 | 0.91 | ALOX5 (0.84) | ALOX5HDAC6 | |
| SCHEMBL9151239 | 0.90 | ALOX5 (0.75) | ALOX5HDAC6 | |
| SCHEMBL9154289 | 0.90 | ALOX5 (0.75) | ALOX5HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100503835-C | Enzyme method for synthesizing (R)-2-cyclopentyl-2-[4-(quinine-2-radical methoxy) phenyl] acetate | UNIV DONGHUA (CN) | 2009-06-24 | — | — | CN | disclosed |
| CN-1814770-A | Enzyme method for synthesizing (R)-2-cyclopentyl-2-[4-(quinine-2-radical methoxy) phenyl] acetate | UNIV DONGHUA (CN) | 2006-08-09 | — | — | CN | disclosed |
| EP-0772594-A1 | IMINOXYCARBOXYLATES AND DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | Abbott Laboratories (US) | 1997-05-14 | — | — | EP | disclosed |
| US-5512581-A | ANTIINFLAMMATORY AGENT | ABBOTT LABORATORIES (US) | 1996-04-30 | — | — | US | disclosed |
| WO-1996002507-A1 | IMINOXYCARBOXYLATES AND DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1996-02-01 | — | — | WO | disclosed |
| US-5358955-A | Antiinflammatory agents | ABBOTT LABORATORIES (US) | 1994-10-25 | — | — | US | disclosed |
| US-4970215-A | Substituted 4-(quinolin-2-yl-methoxy)phenyl-acetic acid derivatives and anti-allergic use thereof | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-13 | — | — | US | disclosed |