Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9151239 | 1.00 | ALOX5 (0.75) | ALOX5HDAC6 | |
| SCHEMBL9124326 | 0.91 | ALOX5 (0.80) | ALOX5HDAC6 | |
| SCHEMBL9431826 | 0.91 | ALOX5 (0.80) | ALOX5HDAC6 | |
| SCHEMBL8827857 | 0.91 | ALOX5 (0.80) | ALOX5HDAC6 | |
| SCHEMBL8827882 | 0.91 | ALOX5 (0.80) | ALOX5HDAC6 | |
| SCHEMBL9430158 | 0.91 | ALOX5 (0.80) | ALOX5HDAC6 | |
| SCHEMBL8799518 | 0.90 | ALOX5 (0.79) | ALOX5HDAC6 | |
| SCHEMBL8892800 | 0.89 | ALOX5 (0.78) | ALOX5HDAC6 | |
| SCHEMBL27629358 | 0.87 | ALOX5 (0.78) | ALOX5HDAC6 | |
| SCHEMBL26838881 | 0.87 | ALOX5 (0.84) | ALOX5HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0666849-A4 | ARYL AND HETEROARYLMETHOXYPHENYL INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS. | ABBOTT LAB (US) | 1995-12-13 | — | — | EP | claimed |
| EP-0666849-A1 | ARYL AND HETEROARYLMETHOXYPHENYL INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1995-08-16 | — | — | EP | claimed |
| US-5358955-A | Antiinflammatory agents | ABBOTT LABORATORIES (US) | 1994-10-25 | — | — | US | claimed |
| WO-1994010148-A1 | ARYL AND HETEROARYLMETHOXYPHENYL INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1994-05-11 | — | — | WO | claimed |
| US-5358955-A | Antiinflammatory agents | ABBOTT LABORATORIES (US) | 1994-10-25 | — | — | US | disclosed |