Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533399 | 0.92 | THRA (0.65) | THRATHRB | |
| SCHEMBL8800887 | 0.87 | THRA (0.62) | THRATHRB | |
| SCHEMBL14366172 | 0.87 | THRA (0.75) | THRATHRB | |
| SCHEMBL23983024 | 0.84 | THRA (0.60) | THRATHRB | |
| SCHEMBL8799243 | 0.84 | THRA (0.59) | THRATHRB | |
| SCHEMBL8799410 | 0.84 | THRA (0.70) | THRATHRB | |
| SCHEMBL7025061 | 0.83 | THRA (0.60) | THRATHRB | |
| SCHEMBL281877 | 0.81 | THRA (1.00) | THRATHRB | |
| SCHEMBL29373673 | 0.81 | THRA (1.00) | THRATHRB | |
| SCHEMBL8799101 | 0.81 | THRB (0.67) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0580550-B1 | Oxamic acid derivatives as hypocholesteremic agents | CIBA GEIGY AG (CH) | 1997-10-22 | — | — | EP | disclosed |
| US-5654468-A | ANTILIPID, ANTICHOLESTEROL AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-08-05 | — | — | US | disclosed |
| US-5569674-A | ANTICHOLESTEROL AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-10-29 | — | — | US | disclosed |
| US-5401772-A | Anticholesterol agents with aromatic amines | CIBA-GEIGY CORPORATION (US) | 1995-03-28 | — | — | US | disclosed |
| EP-0580550-A1 | Oxamic acid derivatives as hypocholesteremic agents | CIBA-GEIGY AG (CH) | 1994-01-26 | — | — | EP | disclosed |