Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 8/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799991 | 0.82 | SIGMAR1 (0.38) | SIGMAR1 | |
| SCHEMBL8799392 | 0.77 | SIGMAR1 (0.37) | SIGMAR1HSD11B1 | |
| SCHEMBL467301 | 0.77 | SIGMAR1 (0.50) | SIGMAR1HSD11B1 | |
| SCHEMBL8800045 | 0.75 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL8908831 | 0.75 | SIGMAR1 (0.73) | SIGMAR1HSD11B1 | |
| SCHEMBL8099379 | 0.75 | SIGMAR1 (0.73) | SIGMAR1HSD11B1 | |
| SCHEMBL8910528 | 0.75 | SIGMAR1 (0.73) | SIGMAR1HSD11B1 | |
| SCHEMBL8908605 | 0.75 | SIGMAR1 (0.73) | SIGMAR1HSD11B1 | |
| SCHEMBL8090048 | 0.75 | SIGMAR1 (0.73) | SIGMAR1HSD11B1 | |
| SCHEMBL8909565 | 0.75 | SIGMAR1 (0.73) | SIGMAR1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650406-A | ANTISCHIZOPHRENIC AGENT | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-07-22 | — | — | US | claimed |
| EP-0757040-A1 | ADAMANTANE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1997-02-05 | — | — | EP | claimed |
| US-5650406-A | ANTISCHIZOPHRENIC AGENT | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-07-22 | — | — | US | disclosed |
| EP-0757040-A1 | ADAMANTANE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1997-02-05 | — | — | EP | disclosed |