Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | CMA1 | P23946 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17048467 | 0.85 | L3MBTL1 (0.67) | KMT2AL3MBTL1ALDH1A1HRH3LMNA | |
| SCHEMBL3459387 | 0.84 | L3MBTL1 (0.64) | KMT2AL3MBTL1CMA1SIGMAR1ALDH1A1 | |
| SCHEMBL8269584 | 0.84 | L3MBTL1 (0.69) | KMT2AL3MBTL1ALDH1A1HRH3LMNA | |
| SCHEMBL20303832 | 0.82 | L3MBTL1 (0.67) | KMT2AL3MBTL1CMA1SIGMAR1ALDH1A1 | |
| SCHEMBL3790844 | 0.82 | PDE4B (0.47) | KMT2AL3MBTL1LMNAMEN1MTNR1A | |
| SCHEMBL27383396 | 0.81 | L3MBTL1 (0.65) | KMT2AL3MBTL1ALDH1A1HRH3TP53 | |
| SCHEMBL13534478 | 0.81 | L3MBTL1 (0.65) | KMT2AL3MBTL1HRH3MEN1GAA | |
| SCHEMBL4509396 | 0.81 | ACACB (0.64) | KMT2AL3MBTL1CMA1SIGMAR1ALDH1A1 | |
| SCHEMBL8799114 | 0.81 | L3MBTL1 (0.53) | KMT2AL3MBTL1HRH3 | |
| SCHEMBL26357193 | 0.80 | KMT2A (0.58) | KMT2ACMA1SIGMAR1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641789-B1 | BENZOTHIADIAZINE DERIVATIVE | TAIHO PHARMACEUTICAL CO LTD (JP) | 1997-12-03 | — | — | EP | disclosed |
| US-5401739-A | Benzothiadiazine derivatives | TAIHO PHARMACEUTICAL CO. LTD. (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0641789-A1 | BENZOTHIADIAZINE DERIVATIVE | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1995-03-08 | — | — | EP | disclosed |