Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 4/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800689 | 0.82 | RAB9A (0.53) | L3MBTL1POLBHRH3APPMCHR1 | |
| SCHEMBL8799862 | 0.81 | KMT2A (0.60) | L3MBTL1HRH3KMT2A | |
| SCHEMBL9551700 | 0.80 | HRH2 (0.59) | HRH2HRH3 | |
| SCHEMBL17048467 | 0.80 | L3MBTL1 (0.67) | L3MBTL1HRH3KMT2A | |
| SCHEMBL10679839 | 0.79 | HRH2 (0.61) | HRH2HRH3 | |
| SCHEMBL5288663 | 0.79 | HRH2 (0.61) | HRH2HRH3 | |
| SCHEMBL10689006 | 0.79 | HRH2 (0.61) | HRH2HRH3 | |
| SCHEMBL30597717 | 0.79 | HRH2 (0.61) | HRH2HRH3 | |
| SCHEMBL10527698 | 0.79 | HRH2 (0.61) | HRH2HRH3 | |
| SCHEMBL8269584 | 0.79 | L3MBTL1 (0.69) | L3MBTL1HRH3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641789-B1 | BENZOTHIADIAZINE DERIVATIVE | TAIHO PHARMACEUTICAL CO LTD (JP) | 1997-12-03 | — | — | EP | disclosed |
| US-5401739-A | Benzothiadiazine derivatives | TAIHO PHARMACEUTICAL CO. LTD. (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0641789-A1 | BENZOTHIADIAZINE DERIVATIVE | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1995-03-08 | — | — | EP | disclosed |