Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | OXTR | P30559 | 7/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CCKBR | P32239 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CCKAR | P32238 | 3/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800443 | 0.94 | CTSB (0.38) | FNTAFNTBOXTRCTSLCTSB | |
| SCHEMBL8801168 | 0.92 | FNTA (0.52) | FNTAFNTBOXTRCTSLCTSB | |
| SCHEMBL8800911 | 0.86 | FNTA (0.45) | FNTAFNTBOXTRCTSLCTSB | |
| SCHEMBL8669842 | 0.83 | CCKBR (0.38) | FNTAFNTBOXTRCTSLCTSB | |
| SCHEMBL8801159 | 0.83 | FNTA (0.60) | FNTAFNTBOXTRCTSLCTSB | |
| SCHEMBL8800669 | 0.82 | FNTA (0.54) | FNTAFNTBOXTRCTSLCTSB | |
| SCHEMBL8801769 | 0.79 | BRD4 (0.37) | FNTAFNTBOXTRCTSLCTSB | |
| SCHEMBL8674131 | 0.78 | HTR2B (0.36) | FNTAFNTBCCKBRKCNH2 | |
| Tetrazole SCHEMBL8801776 | 0.78 | CTSB (0.38) | OXTRCTSLCTSB | |
| SCHEMBL8670222 | 0.78 | FNTA (0.42) | FNTAFNTBOXTRCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994026723-A2 | ras FARNESYL TRANSFERASE INHIBITORS | GENENTECH, INC. (US) | 1994-11-24 | — | — | WO | claimed |
| EP-0763537-A2 | Non-peptidyl Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1997-03-19 | — | — | EP | disclosed |
| EP-0698015-A1 | PREPARATION OF N-CYANODITHIOIMINO-CARBONATES AND 3-MERCAPTO-5-AMINO-1H-1,2,4-TRIAZOLE | GENENTECH, INC. (US) | 1996-02-28 | — | — | EP | disclosed |
| WO-1994026723-A2 | ras FARNESYL TRANSFERASE INHIBITORS | GENENTECH, INC. (US) | 1994-11-24 | — | — | WO | disclosed |