Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL516304 | 0.86 | CA1 (0.36) | TSHRSMN1; SMN2CA1CA2CA9 | |
| SCHEMBL8805212 | 0.79 | CA1 (0.32) | TSHRCA1CA2CA9 | |
| SCHEMBL176317 | 0.78 | CA1 (0.35) | TSHRSMN1; SMN2CA1CA2CA9 | |
| SCHEMBL3684402 | 0.77 | CA1 (0.36) | TSHRCA1CA2CA9MAPT | |
| SCHEMBL5264643 | 0.75 | CA1 (0.30) | CA1CA2CA9 | |
| SCHEMBL93927 | 0.75 | ALDH1A1 (0.44) | TSHRCA1CA2CA9TDP1 | |
| SCHEMBL34317 | 0.75 | CA1 (0.36) | TSHRSMN1; SMN2CA1CA2CA9 | |
| SCHEMBL3697482 | 0.73 | ELANE (0.42) | SMN1; SMN2CA1CA2MAPTTDP1 | |
| SCHEMBL14464519 | 0.73 | HSD17B10 (0.38) | CA1CA2CA9MAPTTDP1 | |
| SCHEMBL6047048 | 0.73 | HPGD (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476930-B1 | Enzyme assays | SANKYO CO (JP) | 1997-11-12 | — | — | EP | claimed |
| EP-0476930-A1 | Enzyme assays | Sankyo Company Limited (JP) | 1992-03-25 | — | — | EP | claimed |
| CN-111051388-B | Hyperbranched polydiorganosiloxane polyoxamide polymers | 3M创新有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-111448182-A | Aztreonam derivative and application thereof | 阿里萨制药有限公司 | 2020-07-24 | — | — | CN | disclosed |
| EP-0476930-B1 | Enzyme assays | SANKYO CO (JP) | 1997-11-12 | — | — | EP | disclosed |
| EP-0476930-A1 | Enzyme assays | Sankyo Company Limited (JP) | 1992-03-25 | — | — | EP | disclosed |