SCHEMBL516304

SCHEMBL516304

O=C(Oc1c(F)c(F)c(F)c(F)c1F)C(=O)Oc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
HSD17B10 Q99714 1/20 0.32
TSHR P16473 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3684402 0.89 CA1 (0.36) CA1CA2CA9HSD17B10TSHR
SCHEMBL8805212 0.86 CA1 (0.32) CA1CA2CA9TSHR
SCHEMBL8800537 0.86 TSHR (0.32) CA1CA2CA9TSHRSMN1; SMN2
SCHEMBL3689925 0.83 ALDH1A1 (0.41) HSD17B10TSHRSMN1; SMN2MAPTTDP1
SCHEMBL17761153 0.83 ELANE (0.32)
SCHEMBL93927 0.82 ALDH1A1 (0.44) CA1CA2CA9TSHRTDP1
SCHEMBL5264643 0.82 CA1 (0.30) CA1CA2CA9
SCHEMBL34317 0.81 CA1 (0.36) CA1CA2CA9HSD17B10TSHR
SCHEMBL28834039 0.80 KMT2A (0.40) HSD17B10SMN1; SMN2
SCHEMBL3697482 0.80 ELANE (0.42) CA1CA2HSD17B10SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119529164-A Thermoplastic acrylic resin slurry for in-situ pultrusion with stable and rapid reaction and preparation method and application thereof 重庆国际复合材料股份有限公司 2025-02-28 CN claimed
US-20250064339-A1 SENSOR DEVICES AND SYSTEMS FOR MONITORING MARKERS IN BREATH BIOLUM SCIENCES LLC (US) 2025-02-27 US claimed
US-11903695-B2 Sensor devices and systems for monitoring markers in breath BIOLUM SCIENCES LLC (US) 2024-02-20 US claimed
CN-116370634-A Nano system for tumor microenvironment-triggered photothermal therapy and preparation method thereof 上海交通大学 2023-07-04 CN claimed
CN-113201804-B Fiber and preparation method thereof 上海邃铸科技有限公司 2023-05-09 CN claimed
CN-113249816-B Transparent fiber and preparation method thereof 上海邃铸科技有限公司 2023-05-05 CN claimed
CN-113214101-B Synthesis method of L-tert-leucine and L-cyclohexylalanine 泰州天鸿生化科技有限公司 2022-05-31 CN claimed
US-20210059560-A1 SENSOR DEVICES AND SYSTEMS FOR MONITORING MARKERS IN BREATH BIOLUM SCIENCES LLC 2021-03-04 US claimed
WO-2019178247-A1 SENSOR DEVICES AND SYSTEMS FOR MONITORING MARKERS IN BREATH BIOLUM SCIENCES LLC (US) 2019-09-19 WO claimed
US-9116147-B2 Compositions and methods for detection of small molecules using dyes derivatized with analyte responsive receptors in a chemiluminescent assay BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2015-08-25 US claimed
US-20120039814-A1 Topical Compositions and Methods of Detection and Treatment JOHNS HOPKINS UNIVERSITY 2012-02-16 US claimed
US-20100144050-A1 HYDROGEN PEROXIDE DETECTOR AND METHODS TELEDYNE FLIR DEFENSE, INC. 2010-06-10 US claimed
WO-2008121124-A1 HYDROGEN PEROXIDE DETECTOR AND METHODS NOMADICS, INC. (US) 2008-10-09 WO claimed
WO-2008062957-A1 1,1'-OXALYLDISODIUMBENZOATE DERIVATIVES, METHOD FOR PREPARATION THEREOF AND CHEMILUMINESCENT COMPOSITION CONTAINING THE SAME LST KOREA. INC. (KR) 2008-05-29 WO claimed
EP-0476930-B1 Enzyme assays SANKYO CO (JP) 1997-11-12 EP claimed
EP-0476930-A1 Enzyme assays Sankyo Company Limited (JP) 1992-03-25 EP claimed
EP-0331077-A2 Method of detecting chemiluminescence by photography DOJINDO LABORATORIES (JP) 1989-09-06 EP claimed
US-4758520-A Chemiluminescence method for assaying compounds containing primary amino groups using 1-cyano-2-substituted benz(f)- or naphth(f)-isoindole fluorescers OREAD LABORATORIES, INC. (US) 1988-07-19 US claimed
EP-0242245-A2 Chemiluminescence method for assaying compounds containing primary amino groups using 1-cyano-2-substituted benz(f)- or naphth(f)isoindole fluorescers OREAD LABORATORIES, INC. (US) 1987-10-21 EP claimed
US-4238195-A Fluorescer-labeled specific binding assays MILES LABORATORIES, INC. (US) 1980-12-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120039814-A1 Topical Compositions and Methods of Detection and Treatment LIPA, TSLP, CUTA CA1 1664/4885CA2 853/4885CA9 582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.