⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8802292 | 0.87 | — | — | |
| SCHEMBL8800948 | 0.67 | — | — | |
| SCHEMBL8800858 | 0.66 | ATR (0.41) | — | |
| SCHEMBL8801148 | 0.64 | — | — | |
| SCHEMBL8800267 | 0.64 | HRH4 (0.30) | — | |
| SCHEMBL9010922 | 0.60 | — | — | |
| SCHEMBL2419807 | 0.60 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL5155534 | 0.60 | CNR2 (0.31) | — | |
| SCHEMBL7364127 | 0.59 | NNMT (0.31) | — | |
| SCHEMBL12322082 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0580916-B1 | N(1) substituted pyrazino [2,3-c]-1,2,6-thiadiazine 2,2-dioxides and their use as pharmaceuticals | PRODESFARMA SA (ES) | 1997-03-05 | — | — | EP | claimed |
| EP-0580916-A1 | N(1) substituted pyrazino 2,3-c -1,2,6-thiadiazine 2,2-dioxides and their use as pharmaceuticals | PRODESFARMA, S.A. (ES) | 1994-02-02 | — | — | EP | claimed |
| EP-0580916-B1 | N(1) substituted pyrazino [2,3-c]-1,2,6-thiadiazine 2,2-dioxides and their use as pharmaceuticals | PRODESFARMA SA (ES) | 1997-03-05 | — | — | EP | disclosed |
| US-5580869-A | DIURETIC, BRONCHODILATOR,AND PLATELET ANTIAGGREGATION ACTIVITY | PRODESFARMA, S.A. (ES) | 1996-12-03 | — | — | US | disclosed |
| EP-0580916-A1 | N(1) substituted pyrazino 2,3-c -1,2,6-thiadiazine 2,2-dioxides and their use as pharmaceuticals | PRODESFARMA, S.A. (ES) | 1994-02-02 | — | — | EP | disclosed |