Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | RHEB | Q15382 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801551 | 0.92 | TDP1 (0.36) | KCNH2TDP1KMT2AP2RX3KDM4E | |
| SCHEMBL5064955 | 0.91 | PIM1 (0.33) | KCNH2TDP1MEN1KMT2ACYP19A1 | |
| SCHEMBL6974146 | 0.90 | ALDH1A1 (0.36) | TDP1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL8800346 | 0.90 | MEN1 (0.32) | KCNH2MEN1KMT2ACYP19A1LMNA | |
| SCHEMBL6975584 | 0.88 | TDP1 (0.34) | TDP1MEN1KMT2ACYP19A1P2RX3 | |
| SCHEMBL8800652 | 0.86 | NPC1 (0.32) | ALDH1A1 | |
| SCHEMBL8800407 | 0.85 | MEN1 (0.33) | MEN1KMT2AP2RX3KDM4EALDH1A1 | |
| SCHEMBL8799639 | 0.85 | GRIN1 (0.35) | MEN1KMT2AP2RX3MAPTALDH1A1 | |
| SCHEMBL8343685 | 0.85 | KCNH2 (0.37) | KCNH2TDP1MEN1KMT2AHTT | |
| SCHEMBL6973011 | 0.84 | MEN1 (0.34) | KCNH2TDP1MEN1KMT2ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |