Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086183 | 0.93 | TP53 (0.35) | KMT2ATP53NOX4ALDH1A1KDM4E | |
| SCHEMBL8800780 | 0.90 | PTGDR2 (0.35) | MEN1KMT2ATP53CNR2ALDH1A1 | |
| SCHEMBL6961698 | 0.89 | S1PR3 (0.38) | ALDH1A1KDM4ES1PR3 | |
| SCHEMBL8799402 | 0.86 | S1PR3 (0.37) | KMT2AALDH1A1S1PR3 | |
| SCHEMBL7083284 | 0.85 | KDM4E (0.34) | MEN1KMT2ATP53NOX4SLC16A3 | |
| SCHEMBL8800746 | 0.85 | KCNH2 (0.35) | MEN1KMT2AP2RX3CNR2ALDH1A1 | |
| SCHEMBL7078972 | 0.84 | SLC16A3 (0.35) | MEN1KMT2ATP53SLC16A3ADRA1D | |
| SCHEMBL6974146 | 0.83 | ALDH1A1 (0.36) | MEN1KMT2ATP53NOX4SLC16A3 | |
| SCHEMBL8800655 | 0.83 | CFTR (0.41) | MEN1KMT2AALDH1A1KDM4EMAPK1 | |
| SCHEMBL8800652 | 0.83 | NPC1 (0.32) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |